Journals
  • Krittika Nandy, Dinesh Babu, Sonam Rani, Gaurav Joshi, Smitha Ijee, Anila George, Dhavapriya Palani, Chitra Premkumar, Praveena Rajesh, S. Vijayanand, Ernest David, Mohankumar Murugesan & Shaji R. Velayudhan. Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression. Sci Rep 13, 21953 (2023). https://doi.org/10.1038/s41598-023-42174-2.
  • Ravi NS, George A, Mohankumar KM. Protocol for arrayed gRNA screening by base editors in mammalian cell lines using lentiviral system. STAR Protoc. 2023 Nov 2;4(4):102668. doi: 10.1016/j.xpro.2023.102668. Epub ahead of print. PMID: 37922314.
  • Elizabeth Vinod, Ganesh Parasuraman, Abel Livingston, Soosai Manickam Amirtham, Grace Rebekah, Jeya Lisha J, Alfred Job Daniel, Solomon Sathishkumar. Comparison of methods for the isolation and culture of Migratory Chondroprogenitors from Human articular cartilage. . Connect Tissue Res . 2023 Jul;64(4):389-399.
  • Agnes Selina. Deeptiman James, Vrisha Madhuri. A Novel Biallelic Splice Site Variant in the SPARC Gene Causing Severe Osteogenesis Imperfecta. Indian J Pediatr . 2023 Jun;90(6):626.
  • Raina K, Joshi G, Modak K, Premkumar C, Priyanka S, Rajesh P, Velayudhan SR,Thummer RP. Generation and characterization of induced pluripotent stem cell line IITGi001-A derived from adult human primary dermal fibroblasts. Stem Cell Res. 2023 Jun 28;71:103159. doi: 10.1016/j.scr.2023.103159.
  • Rani, S., Thamodaran, V., Nandy, K., Fouzia, N. A., Maddali, M., Rajesh, P., Velayudhan, S. R. Establishment and characterization of CSCRi006-A: an induced pluripotent stem cell line generated from a patient with Diamond-Blackfan Anemia (DBA) carrying ribosomal protein S19 (RPS19) mutation. Human Cell, 36(6), 2204-2213 (2023). doi: 10.1007/s13577-023-00946-y
  • Esther Sathya Bama Benjamin, Dinesh Babu, Gaurav Joshi, Bharathi M Rajamani, Krittika Nandy, Sonam Rani, Senthamizhselvi Anandan, Chitra Premkumar, Madhavi Maddali, Aby Abraham, Shaji R Velayudhan, Poonkuzhali Balasubramanian. Inhibition of BCR::ABL1 tyrosine kinase activity Aids in the Generation of Stable Chronic Myeloid Leukemia Induced Pluripotent Stem Cells. bioRxiv 2023.06.01.543015; doi: https://doi.org/10.1101/2023.06.01.543015 .
  • Gokulnath M, Porkizhi A, Yogapriya P, Ajay D, Nivedita D, Vignesh R, Abhisha C, Ramya Devi KT2, Immanuel D, Saravanabhavan T, Mohankumar M, Mahesh M, Alok S, Srujan M, Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor. Scientific Reports 2023 May30.13(1):8743.
  • Elizabeth Vinod, Jeya Lisha J, Ganesh Parasuraman, Abel Livingston, Alfred Job Daniel, Solomon Sathishkumar. Evaluation of Ghrelin as a distinguishing marker for human articular cartilage-derived chondrocytes and chondroprogenitors. Journal of Clinical Orthopaedics and Trauma. 2023 May 29;41:102175.
  • Rajamani BM, Illangeswaran RSS, Benjamin ESB, Balakrishnan B, Jebanesan DZP, Das S, Pai AA, Vidhyadharan RT, Mohan A, Karathedath S, Abraham A, Mathews V, Velayudhan SR, Balasubramanian P. Modulating retinoid-X-receptor alpha (RXRA)expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo. Front Pharmacol. 2023 May 31;14:1187066.
  • Alok Srivastava, Savita Rangarajan, Kaan Kavakli, Robert Klamrot, Gili Kenet, Liane Khoo, Chur-Woo You, Weiqun Xu , Niel Malan, Laurent Frenzel, Catherine N Bagot, Oleksandra Stasyshyn, Chia-Yau Chang, Stacey Poloskey, Zhiying Qiu, Shauna Andersson, Baisong Mei and Steven W Pipe . Fitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B): a multicentre, open-label, randomised, phase 3 trial. Lancet Haematol . 2023 May;10(5):e322-e332.  DOI:https://doi.org/10.1016/S2352-3026(23)00037-6.
  • George, A., Ravi, N. S., Vaishnavi, B., Marepally, S., Thangavel, S., Velayudhan, S. R., .Mohankumar, K. M. (2023). Editing of highly homologous gamma-globin genes by nickase deficient Base Editor mitigates large intergenic deletions: Cold Spring Harbor Laboratory. bioRxiv 2023.12.04.569931; doi: https://doi.org/10.1101/2023.12.04.569931
  • Elizabeth Vinod, Ganesh Parasuraman, Jeya Lisha J, Soosai Manickam Amirtham, Abel Livingston, Jithu James Varghese, Sandya Rani, Deepak Vinod Francis, Grace Rebekah, Alfred Job Daniel, Boopalan Ramasamy, Solomon Sathishkumar. Human fetal cartilage-derived chondrocytes and chondroprogenitors display a greater commitment to chondrogenesis than adult cartilage resident cells. PLoS One . 2023 Apr 27;18(4):e0285106.
  • Venkatesan V, Christopher AC, Rhiel M, Azhagiri MKK, Babu P, Walavalkar K, Saravanan B, Andrieux G, Rangaraj S, Srinivasan S, Karuppusamy KV, Jacob A, Bagchi A, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Pai R, Marepally SK, Mohankumar KM, Velayudhan SR, Boerries M, Notani D, Cathomen T, Srivastava A, Thangavel S. Editing the core region in HPFH deletions alters fetal and adult globin expression for the treatment of β-hemoglobinopathies. Mol Ther Nucleic Acids. 2023 Apr 26;32:671-688. doi: 10.1016/j.omtn.2023.04.024. PMID: 37215154; PMCID: PMC10197010.
  • Guy Young, Alok Srivastava, Kaan Kavakli, Cecil Ross, Jameela Sathar, Chur-Woo You, Huyen Tran, Jing Sun, Runhui Wu, Stacey Poloskey, Zhiying Qiu, Salim Kichou, Shauna Andersson, Baisong Mei, Savita Rangarajan. Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH): a multicentre, open-label, randomised phase 3 trial. Lancet . 2023 Apr 29;401(10386):1427-1437. DOI:https://doi.org/10.1016/S0140-6736(23)00284-2.
  • Raveen Stephen, Stallon Illangeswaran, Daniel Zechariah Paul Jebanesan , Kezia Kanimozhi Sivakumar , Rakhi Thalayattu Vidhyadharan , Bharathi M. Rajamani , Nancy Beryl Janet , Ernest David , Shaji Ramachandran Velayudhan, Vikram Mathews , Poonkuzhali Balasubramanian. Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines. Leukemia Research, Volume 128, May 2023. (https://www.sciencedirect.com/science/article/abs/pii/S0145212623000395?via%3Dihub)
  • Gaurav Joshi, Nancy Bery, Janet Arthur , Thenral S Geetha , Phaneendra Venkateswara Rao Datari , Kirti Modak , Debanjan Roy , Anurag Dutta Chaudhury , Prasanth Sundaraganesan , Sweety Priyanka , Fouzia Na , Vedam Ramprasad , Aby Abraham , Vivi M Srivastava , Alok Srivastava , Uday Prakash Kulkarni , Biju George , Shaji R Velayudhan. Comprehensive laboratory diagnosis of Fanconi anaemia: comparison of cellular and molecular analysis. J Med Genet. 2023 Mar 9; jmedgenet-2022-108714. doi: 10.1136/jmg-2022-108714. Online ahead of print.
  • Hemalatha R, Muthuraman N, Sandya Rani, Premila Abraham. A study on the alteration of endoplasmic reticulum stress related proteins in cyclophosphamide induced damage to urothelium. Pharmaceutical and Biomedical research on 31.01.2023.
  • Lohchania B, Christopher A, Arjunan P, Mahalingam G, Kathirvelu D, Prasannan A, Venkatesan V, Taneja P, Mohan Kumar Km , Thangavel S , Marepally S ."Diosgenin enhances liposome-enabled nucleic acid delivery and CRISPR/Cas9-mediated gene editing by modulating endocytic pathways. Front Bioeng Biotechnol. 2023 Jan 9;10:1031049. doi: 10.3389/fbioe.2022.1031049.
  • Mahalingam G, Periyasami Y, Arjunan P, Subaschandrabose RK, Mathivanan TV, Mathew RS, Ramya Devi K, Premkumar PS, Muliyil J, Srivastava A, Moorthy M*, Marepally S*. Omicron infection increases IgG binding to spike protein of predecessor variants. J Med Virol . 2023 Feb;95(2):e28419. doi: 10.1002/jmv.28419.
  • Francis, D. V., Rajeswari, A. J., Stephen, J. B., Parasuraman, G., Lisha J, J., Livingston, A.,Vinod, E. An ultrastructural report of human articular cartilage resident cells in correlation with their phenotypic characteristics. Journal of Histotechnology, 47(1), 23-38, 2023. doi: 10.1080/01478885.2023.2278118.
  • Murugesan, R., Karuppusamy, K. V., Marepally, S., & Thangavel, S. (2023). Current approaches and potential challenges in the delivery of gene editing cargos into hematopoietic stem and progenitor cells. Frontiers in genome editing, 5, 1148693-1148693. doi: 10.3389/fgeed.2023.1148693.
  • Parasuraman, G., Vinod, E., Livingston, A., Sathishkumar, S., & Francis, D. V. Comparative assessment of the morphology and antigenicity of human osteochondral units using formalin and coagulant fixatives. European Journal of Anatomy, 705-716, 2023. doi: 10.52083/cvzf3774.