Paper Accepted:
  • Ayshath Ruksana C, Mohana Priya, Archa Suresh, Ganesh Parasuraman, Grace Rebekah, Christo Jeyaraj, Elizabeth Vinod. Preliminary insights into Temporal Expression Patterns of α10β1, α5β1, and α2β1 Integrins in Freshly Isolated Chondrocytes: Potential Impacts on Cartilage Repair Strategies. European Journal of Anatomy. Accepted on 19th Nov 2024.
  • Ganesh Parasuraman, Mariya Sneha Rani J, Merin Mary Zachariah, Abel Livingston, Elizabeth Vinod. Matrigel-Encapsulated Articular cartilage derived fibronectin adhesion assay derived Chondroprogenitors for Enhanced Chondrogenic Differentiation: An In Vitro Evaluation. . Tissue and Cell . Accepted on 20th Nov 2024.
  • Prathibha Babu Chandraprabha; Manoj Kumar K Azhagiri; Vigneshwaran Venkatesan; Wendy Magis; Kirti Prasad; Sevanthy Suresh; Aswin Anand Pai; Srujan Marepally; Alok Srivastava; Kumarasamypet Murugesan Mohankumar; David IK Martin; Saravanabhavan Thangavel. Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies. Journal: Stem Cell Research & Therapy
Paper Published:
  • Elizabeth Vinod, Ganesh Parasuraman, Abel Livingston, Grace Rebekah, Solomon Sathishkumar. Exploring Ghrelin Hormone Secretagogue Receptor and Membrane-Bound Ghrelin O-Acyl Transferase as Potential Markers for Chondrogenesis in Human Articular Cartilage-Derived Cells. European Journal of Anatomy. Nov 2024 https://doi.org/10.52083/ZYHX7619.
  • Rachamala HK, Marepally S* Multiplexed RNAs in lipid nanoparticles: potential therapeutic vaccine for chronic hepatitis B. Signal Transduct Target Ther. 2024 Nov 7;9(1):312. doi: 10.1038/s41392-024-02026-5.
  • Brijesh Lohchania, Porkizhi Arjunan, Gokulnath Mahalingam, Abinaya Dandapani, Pankaj Taneja* and Srujan Marepally* Lipid Nanoparticle-Mediated Liver-Specific Gene Therapy for Hemophilia B. Pharmaceutics 2024, 16, 1427. https://doi.org/10.3390/ pharmaceutics16111427
Invited talk
  • Dr Saravanabhavan Thangavel delivered a talk titled “Engineering extracellular vesicles" at EXOVIT2024 workshop, VIT, Vellore on 24/10/2024.
  • Dr. Thiyagaraj M delivered a talk titled “Cell based assays for characterization and culture of hematopoietic stem cells for preclinical studies” at ICMR-DHR sponsored support for conducting a training program on modern biology in health research at Mahatma Gandhi Medical and Advanced Research Institute (MGMARI), SBV, Pondicherry, India on October 21, 2024.
Event:

Title of the talk: Stem cell manufacturing and gene modifications
Speaker: Dr Darren Tan
Affiliation: Miltenyi Biotech, Germany
Date and time: 19th Nov 2024, Tuesday, 11 AM (IST)
Number of participant's: 40 (In Person)
Coordinated by: Dr. Gurbind Singh and Core lab

Outreach

Dr Saravanabhavan Thangavel gave 3 classes on "gene edited stem cell therapy" to the M.Tech students of MAHE - Manipal Academy of Higher Education.

Other updates:

Dr. Elizabeth Vinod has been nominated as an Expert Stem Cell Member for the Institutional Ethics Committee of IIT Madras (November 2024-present).
Conference Participation Update
Event: IAS Frontiers Conference on Genome Engineering
Date: November 13–15, 2024
Venue: Nanyang Technological University, Singapore
Participant: Anila George

Award Update

Award: Best Poster Award
Awarded to: Anila George
Poster Title: Nickase Deficient Base Editor Mitigates Interstitial Deletions in HSPCs During Multiplexed Editing and Editing of Homologous Sites
Event: Poster presentation at the IAS Frontiers Conference on Genome Engineering, Singapore.