Given the translational mandate at CSCR and the clinical needs and interests at the Christian Medical College, Vellore, there are several other areas of translational research that are also being pursued at CSCR. The following are the list of current projects:
- Dr. Christhunesa S. Christudass, Associate Professor – Neurochemistry, Department of Neurological Sciences, CMC, Vellore: Isolation of cancer stem cells from primary and secondary high-grade gliomas - their response to microenvironmental cues and Notch signaling blockade. (Funding source: Department of Biotechnology, Government of India)
- Dr. Inian Samarasam, Professor and Head, Upper GI Surgery Unit, Department of Surgery - Unit 3, CMC, Vellore: Tissue regeneration using muscle derived stem cells in the treatment of ventral hernia in a rat model. (Funding source: CSCR Core Grant)
- Dr. Jeyanth Rose, Associate Professor, Department of Ophthalmology-Schell Eye Hospital, CMC, Vellore: Efficacy of placenta derived Mesenchymal Stem Cells in reducing corneal scarring in an Ex-vivo organ culture model of post mortem human corneas / A Bioengineered corneal substitute using decellularized human donor cornea rejected for corneal transplant. (Funding source: CMC Fluid grant / CSCR)
- Dr. Poonkuzhali Balasubramanian, Professor, Department of Haematology, CMC, Vellore: To evaluate the role of epigenetic factors in drug resistance in acute myeloid leukemia by shRNA library screening / Identification of novel nuclear receptor (NHR) drug targets in myeloid leukemias. (Funding source: Department of Biotechnology, Government of India [Part of Centre of Excellence Grant])
- Dr. Geeta Chacko, Professor, Department of Pathology, CMC, Vellore: C11orf95-RELA fusions in supratentorial ependymomas: Relevance in prognostication. (Funding source: Department of Science and Technology, Government of India)
- Dr. Boopalan Ramasamy, Professor, Department of Orthopedics Unit III, CMC Vellore: In vitro characterization and immunogenic profiling of human articular chondroprogenitor cells from normal and osteoarthritic knee joints. (Funding source: AO Trauma Asia Pacific Research Grant)
- Dr. Aby Abraham, Professor, Department of Haematology, CMC Vellore: Gamma delta T cell-based immunotherapy for blood cancers / Establishing a protocol for expansion of Natural Killer cells. (Funding source: CSCR Core Grant)
- Dr. Elizabeth Vinod, Assistant Professor, Department of Physiology, CMC Vellore: Chondroprogenitor cells in Platelet Rich Plasma for treatment of osteoarthritis and osteochondral defects in rabbit knee model. (Funding source: CSCR Core Grant)
- Dr. Muthuraman N, Assistant Professor, Department of Biochemistry, CMC Vellore: Isolation and characterization of cancer stem like cells of human primary endometrial cell culture derived from type I and type II endometrial cancer tissue from patients. (Funding source: CSCR Core Grant)