09:45 to 09:50 AM

09:50 to 10:00 AM

10:00 to 10:10 AM

· Prayer

· Welcome and introductory remarks: Dr. J. V. Peter, Director / Dr. Anna Pulimood, Principal, CMC / Dr. Alok Srivastava, Head, CSCR

· Remarks by Dr. Renu Swarup, Secretary, Department of Biotechnology, Ministry of Science and Technology, Govt. of India

Session-1: TECHNOLOGY ADVANCES

Moderator: Vijay Chandru

10:15 to 10:45AM

AAV8 gene therapy for hemophilia B

Lakshmikanth Gandikota

Intas Pharmaceuticals, India

10:45 to 11:15AM

Studying DNA repair diseases using iPSCs

R V Shaji

Centre for Stem Cell Research, and Christian Medical College Vellore, India

11:15 to 11:45AM

Neutral lipopolyplexes for in vivo delivery of conventional and self-amplifying RNA vaccine

Chantal Pichon

University of Orléans, France

11:45 to 12:00PM

Break

KEYNOTE ADDRESS

Moderator: Alok Srivastava

12:00 to 01:00PM

Gene therapy for hemoglobin disorders – What it has been and what it will be?

Marina Cavazzana

Necker-Enfants Malades Hospital and  Institut Imagine, France

01:00 to 2:00PM

Poster session

Session-2: GENE EDITING

Moderator: Jyotsna Dhawan

02:00 to 2:30PM

Editing approaches for the treatment of β-hemoglobinopathies

Annarita Miccio

Institut Imagine, France

02:30 to 3:00PM

Cas9-mediated correction of sickle mutation: Towards a clinical trial

David Martin

Children’s Hospital Oakland Research Institute, USA

03:00 to 3:30PM

Identification of novel HPFH-like mutations by CRISPR base editing that elevates the expression of fetal hemoglobin

Mohankumar Murugesan

Centre for Stem Cell Research, India

03:30 to 3:45PM

Break

Session-3:  APPLICATIONS OF iPSC TECHNOLOGY

Moderator: Indumathi Mariappan

03:45 to 4:15PM

Quality control guidelines for the iPSCs for clinical applications

Glyn Stacey

International Stem Cell Banking

Initiative, UK

04:15 to 4:45PM

Eyecyte-RPE from bench to bedside- The Eyestem story

Jogin Desai

Eyestem Research Pvt. Ltd., India

04:45 to 5:15PM

Autologous iPS cell based therapy for macular degeneration

Kapil Bharti

National Institutes of Health, USA

05:15 to 05:30PM

Break

Session-4: GENE THERAPY

Moderator: Mammen Chandy

05:30 to 6:00PM

Phagocytosis-shielded lentiviral vectors for liver gene therapy of hemophilia

Alessio Cantore

San Raffaele Telethon Institute for Gene Therapy, Italy

06:00 to 6:30PM

Development of NextGen AAV6 vectors for the potential gene therapy and genome editing of human hemoglobinopathies

Arun Srivastava

University of Florida

College of Medicine, USA

06:30 to 7:00PM

Activation of gamma globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin

Mitchell Weiss

St. Jude Children’s Research Hospital, USA

7:00 to 7:15PM

Break

Session-5: MANUFACTURING AND REGULATORY ASPECTS IN CELL AND GENE THERAPY

Moderator: Navin Khattry

7:15 to 7:45PM

Manufacturing considerations for fresh, autologous mesenchymal stromal cells for osteoarthritis

Sowmya Viswanathan

University Health Network, Canada

7:45 to 8:15PM

Manufacturing of lentiviral vectors for gene therapy

William Swaney

Expression Therapeutics, USA

8:15 to 8:45PM

cGMP manufacturing of cell and gene therapies

Neehar Bhatia

Stanford University, USA

Session-6: IMMUNE CELL THERAPY

Moderator: Apurva Sarin

8:00 to 8:30AM

Engineering gamma delta T cells for cancer immunotherapy

Trent Spencer

Emory University

School of Medicine, USA

8:30 to 9:00AM

Flexible, clinically adaptable, non-viral approaches to CAR-TCR methodologies

Rama Shivakumar

MaxCyte Inc.,USA

9:00 to 9:30AM   

CAR journey in India: Discovery to Clinic

Rahul Purwar

Indian Institute of Technology Bombay, India

9:30 to 9:45AM

Break

Session-7: CELL THERAPY IN MUSCULOSKELETAL DISORDERS

Moderator: Prabha Nair

09:45 to 10:15AM

Placenta-derived Mesenchymal Stromal Cells for in utero repair of Myelomeningocele

Priyadarsini Kumar

University of California, Davis, USA

10:15 to 10:45AM

Skeletal tissue regeneration: The past and the future

Vrisha Madhuri

Centre for Stem Cell Research and Christian Medical College Vellore, India

10:45 to 11:15AM

Next generation innovative stem cell-based and cell-free therapeutics for Osteogenesis imperfecta

Pascale Guillot

University College London, UK

11:15 to 11:30AM

Break

Session-8: MESENCHYMAL STROMAL CELL-BASED THERAPY

Moderator: Sujata Mohanty

11:30 to 12:00PM

Stem cell gene therapy for skin regeneration

Amitava Das

CSIR-Indian Institute of Chemical Technology, India

12:00 to 12:30PM

Allogeneic Mesenchymal Stromal Cells Product – Stempeucel – approved in India for Critical Limb Ischemia

Pawan Kumar Gupta

Stempeutics Research Pvt. Ltd., India