9th Annual Cell and Gene Therapy Symposium

Centre for Stem Cell Research (a unit of inStem, Bengaluru), Christian Medical College Campus, Vellore

CGTS 2019

PROGRAMME SCHEDULE

DAY-1: THURSDAY, 05TH SEPTEMBER, 2019

8:00 to 8:45AM: REGISTRATION

8:45 to 8:50AM

 

8:50 to 9:00AM

 

9:00 to 9:05AM

 

9:05 to 9:10AM

 

 

9:10 to 9:15AM

 Prayer

 

Welcome and introductory remarks – Dr. J. V. Peter, Director / Dr. Anna Pulimood, Principal, CMC

 

Address by Dr. Renu Swarup, Secretary, Department of Biotechnology (DBT), Govt. of India

 

Address by Dr. Balram Bhargava, Secretary, Department of Health Research (DHR), Govt. of India & Director General, Indian Council of Medical Research (ICMR)

 

Address by Dr. V. G. Somani, Drug Controller General (India), Central Drugs Standard Control Organisation (CDSCO), Govt. of India
Session-1:  IMMUNE CELL THERAPY
Chair: Shubhada Chiplunkar
9:20 to 9:25AM Introduction to the session
9:25 to 9:55AM Developing ligand-based chimeric antigen receptors to target leukemic and bone marrow stem cells Trent Spencer

Emory University

School of Medicine, USA
9:55 to 10:25AM Translating indigenous CAR T cell therapy from lab to clinic Rahul Purwar

Indian Institute of Technology Bombay, India
10:25 to 10:55AM Third party antigen specific T cells for treatment of virus infections after allogeneic stem cell transplant David Gottlieb

Westmead Hospital Sydney, Australia
10:55 to 11:25AM Tea / Coffee Break
Session-2:  APPLICATIONS OF iPSC TECHNOLOGY
Chair: Raghu Padinjat
11:25 to 11:30AM Introduction to the session
11:30 to 12:00PM International quality standards for clinical-grade induced pluripotent stem cells Stephen Sullivan

Global Alliance for iPSC Therapies, UK
12:00 to 12:30PM Clinically compliant culture systems for the iPSC work flow Roland Leathers

Thermo Fisher Scientific,

Switzerland
12:30 to 1:00PM Application of iPSCs for understanding the molecular basis of neurological diseases Odity Mukherjee

Institute for Stem Cell Science and Regenerative Medicine, India
1:00 to 2:00PM Lunch
Session-3: TECHNOLOGY ADVANCES
Chair: Rita Mulherkar
2:00 to 2:05PM Introduction to the session
2:05 to 2:35PM Development of AAV vectors capable of evading neutralizing antibodies and dampening the host humoral immune response

 

 Arun Srivastava

University of Florida

College of Medicine, USA
2:35 to 3:05PM CRISPR 2.0: Tackling the specificity problem Debojyoti Chakraborty

CSIR-Institute of Genomics and Integrative Biology, India
3:05 to 3:35PM Vector manufacturing for bench vs bedside: Bridging the chasm between preclinical and clinical manufacturing strategies Trent Spencer

Emory University

School of Medicine, USA
3:35 to 4:35PM Tea / Coffee Break with Poster Session
 

 

Session-4: MANUFACTURING AND REGULATORY ASPECTS IN CELL AND GENE THERAPY
Chair: Thangarajan Rajkumar
4:35 to 4:40PM Introduction to the session
4:40 to 5:10PM Good manufacturing practice for pluripotent stem cell for clinical grade application Mahendra Rao

Institute for Stem Cell Science and Regenerative Medicine, India
5:10 to 5:40PM Quality control for hPSC lines and hPSC-based products Glyn Stacey

International Stem Cell Banking

Initiative, UK
5:40 to 6:10PM Manufacturing of advanced therapy medicinal products in a European academic setting Pontus Blomberg

Karolinska Institutet and Karolinska University Hospital, Sweden
KEY NOTE ADDRESS
Chair: Alok Srivastava
6:10 to 6:15PM Introduction
6:15 to 7:15PM Evolution of T- cell therapy for infections David Gottlieb

Westmead Hospital Sydney, Australia
7:15PM onwards Dinner

DAY-2: FRIDAY, 06TH SEPTEMBER, 2019

Session-5: GENE EDITING
Chair: R V Shaji
8:00 to 8:05AM Introduction to the session
8:05 to 8:35AM High-level Cas9-mediated correction of the sickle mutation in human hematopoietic stem cells David Martin

Children’s Hospital Oakland Research Institute, USA
8:35 to 9:05AM Rewinding the internal clock of hemoglobin synthesis in adult stem cells Sivaprakash Ramalingam

CSIR-Institute of Genomics and Integrative Biology, India
9:05 to 9:35AM Therapeutic Gene editing at the β-globin locus Sowmya Pattabhi

Seattle Children’s Research Institute, USA
9:35 to 10:05AM Crispr-Cas9 mediated HPFH like mutations for fetal hemoglobin reactivation Saravanabhavan Thangavel

Centre for Stem Cell Research, India
10:05 to 11:05AM Tea / Coffee Break with Poster Session
 

 

Session-6: GENE THERAPY
Chair: Alok Srivastava
11:05 to 11:10AM Introduction to the session
11:10 to 11:40AM Emerging roles of transgene mutations in gene therapy products for hemophilia Christopher Doering

Emory University

School of Medicine, USA
11:40 to 12:10PM The role of miRNA17-92 cluster in AAV vector-mediated transgene expression Arun Srivastava

University of Florida

College of Medicine, USA
12:10 to 12:40PM Next-generation gene therapy and gene editing for muscle disorders Thierry VandenDriessche

Free University of Brussels & University of Leuven, Belgium
12:40 to 1:10PM Targeting erythroid specific BCL11A enhancer in hematopoietic stem and progenitor cells for the therapeutic induction of fetal hemoglobin Mohankumar Murugesan

Centre for Stem Cell Research, India
1:10 to 2:10PM Lunch
 

 

Session-7: CELL THERAPY IN OCULAR DISORDERS
Chair: Arkasubhra Ghosh
2:10 to 2:15PM Introduction to the session
2:15 to 2:45PM Limbal derived stem cells in corneal and limbal wound healing Vivek Singh

L.V. Prasad Eye Institute,

India
2:45 to 3:15PM Cell Therapy of corneal diseases with umbilical mesenchymal stem / stromal cells Winston W-Y Kao

University of Cincinnati, USA
3:15 to 3:45PM Retinal cell replacement in macular degeneration: A pluripotent stem cell-based approach Rajarshi Pal

Eyestem Research Private Limited, India
3:45 to 4:00PM Conclusion remarks

CGTS 2019 ABSTRACT BOOK – Click to view / download

CGTS 2019 SCIENTIFIC PROGRAM – Click to view / download