Centre for Stem Cell Research

Papers accepted

• Upasana Kachroo, Elizabeth Vinod. Comparative analysis of gene expression between articular cartilage derived cells to assess suitability of fibronectin adhesion assay to enrich chondroprogenitors. The Knee (16th April 2020).
• Elizabeth Vinod, Boopalan Ramasamy and Upasana Kachroo. Evaluation of CD49e as a distinguishing marker for human articular cartilage derived chondroprogenitors. The Knee (04th April 2020).
• Elizabeth Vinod, Tephilla Epsibha Jefferson, Soosai Manickam Amirtham, Neetu Prince, Tulasi Geevar, Grace Rebekah, Boopalan Ramasamy, Upasana Kachroo. Correlation between synovial fluid calcium containing crystal estimation and varying grades of Osteoarthritis using a rabbit model: Potential diagnostic tool.Journal of Clinical Orthopaedics and Trauma (31st March 2020.

Papers published

• Elizabeth Vinod, Tephilla Epsibha Jefferson, Soosai Manickam Amirtham, Neetu Prince, Tulasi Geevar, Grace Rebekah, Boopalan Ramasamy, Upasana Kachroo. Correlation between synovial fluid calcium containing crystal estimation and varying grades of Osteoarthritis using a rabbit model: Potential diagnostic tool. Journal of Clinical Orthopaedics and Trauma. (07th April 2020)
• Elizabeth Vinod, Boopalan Ramasamy, Upasana Kachroo. Comparison of immunogenic markers of human chondrocytes and chondroprogenitors derived from non-diseased and osteoarthritic articular cartilage. Journal of Orthopaedics, Trauma and Rehabilitation (03rd April 2020).

Papers accepted

• Elizabeth Vinod, Roshni Parameswaran, Soosai Manickam Amirtham, Abel Livingston, Boopalan Ramasamy, Upasana Kachroo . Comparison of the efficiency of laminin versus fibronectin as a differential adhesion assay for isolation of human articular cartilage derived chondroprogenitors. Connective Tissue Research (21st April 2020).

Papers published

• Elizabeth Vinod, Roshni Parameswaran, Soosai Manickam Amirtham, Abel Livingston, Boopalan Ramasamy, Upasana Kachroo . Comparison of the efficiency of laminin versus fibronectin as a differential adhesion assay for isolation of human articular cartilage derived chondroprogenitors. Connective Tissue Research (14th May 2020).
• Upasana Kachroo, Shikha Mary Zachariah, Augustine Thambaiah, Aleya Tabasum, Abel Livingston, Grace Rebekah, Alok Srivastava and Elizabeth Vinod. Comparison of human platelet lysate versus fetal bovine serum for expansion of human articular cartilage derived chondroprogenitors. Cartilage. (14th May 2020).
• Upasana Kachroo, Boopalan Ramasamy, Elizabeth Vinod . Evaluation of CD49e as a distinguishing marker for human articular cartilage derived chondroprogenitors. The Knee (18th April 2020).

Patents filed

• Inventors : Dr. Mohankumar Murugesan, Dr. Alok Srivastava

Jurisdiction : Filed in India (other countries to be decided)

Temp. Application No. : TEMP/E-1/21886/2020-CHE

Title : Compositions and methods for reactivating developmentally silent genes

Date of filing : 13th May, 2020

Papers accepted:

• Elizabeth Vinod, Upasana Kachroo, Grace Rebekah, Bijesh Kumar Yadav and Boopalan Ramasamy. Characterization of human articular chondrocytes and chondroprogenitors derived from non-diseased and osteoarthritic knee joints to assess superiority for cell-based therapy. Acta Histochemica. 27th June 2020.

Papers published:

• Upasana Kachroo and Elizabeth Vinod. Comparative analysis of gene expression between articular cartilage-derived cells to assess suitability of fibronectin adhesion assay to enrich chondroprogenitors. The Knee Volume 27, Issue 3, June 2020, Pages 755-759.

Paper published

• Elizabeth Vinod, Upasana Kachroo, Grace Rebekah, Bijesh Kumar Yadav and Boopalan Ramasamy. Characterization of human articular chondrocytes and chondroprogenitors derived from non-diseased and osteoarthritic knee joints to assess superiority for cell-based therapy. Acta Histochemica. 7th July 2020.
• Harrison C. Brown, Christopher B. Doering, Roland W. Herzog, Chen Ling, David M. Markusic, H. Trent Spencer, Alok Srivastava, and Arun Srivastava. Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B. Human Gene Therapy. 12th July 2020.

Paper published

• Elizabeth Vinod, Roshni Parameswaran, Boopalan Ramasamy and Upasana Kachroo. "Pondering the potential of hyaline cartilage derived chondroprogenitors for tissue regeneration: A systematic review" CARTILAGE accepted on 21.07.2020.

Paper published

• Elizabeth Vinod, Roshni Parameswaran, Boopalan Ramasamy and Upasana Kachroo. "Pondering the potential of hyaline cartilage derived chondroprogenitors for tissue regeneration: A systematic review" CARTILAGE - August 25, 2020

Accepted:

• Elizabeth Vinod, Upasana Kachroo, Grace Rebekah,Thomas and Boopalan Ramasamy. In vitro chondrogenic differentiation of human articular cartilage derived chondroprogenitors using pulsed electromagnetic field. Journal of Clinical Orthopaedics and Trauma. Accepted on 30.09.2020

Published:

• Karthikeyan Rajagopal, Sowmya Ramesh, Noel Malcolm Walter, Aditya Arora, Dhirendra S.Katti, and Vrisha  Madhuri. In vivo cartilage regeneration in a multi-layered articular cartilage architecture mimicking scaffold. Bone Joint Research. Published on 21.09.2020

Papers accepted:

• Hubert D-J Daniel, Sanjay Kumar, Rajesh Kannangai, Kavitha M Lakshmi, Mavis Agbandje-Mckenna, Kirsten Coleman, Arun Srivastava, Alok Srivastava, Asha Mary Abraham. Prevalence of AAV3 capsid binding and neutralizing antibodies in healthy and individuals with hemophilia B from India - accepted on 11-Nov-2020.

Published:

• Case report of a PRDM5 linked brittle cornea syndrome type 2 in association with a novel SLC6A5 mutation. Selina A, John D, Loganathan L, Madhuri V. Indian J Ophthalmol. 2020 Nov;68(11):2545-2547. 26-Oct-2020.
• Manipulation of developmental gamma-globin gene expression: an approach for healing hemoglobinopathies. Vigneshwaran Venkatesan, S Srinivasan, P Babu, S.Thangavel  - Molecular and Cellular Biology, 2020 - 19-Oct-2020 (published online).

Patent filed:

• Substituted Lithocholic Acid and Methods Thereof. Filed 29.10.2020. Application No. 202041047355